E1s/E2s
Catalog number: SBB-CE0011, 50 µg
UBA1 is the canonical Ubiquitin E1 activating enzyme, which catalyzes the first step of the Ubiquitin conjugation cascade. UBA1 charges Ubiquitin to a thioester on its active site cysteine through an adenylate intermediate.[1][2][3][4]
Catalog number: SBB-CE0058, 50 µg
UBA1 is the canonical Ubiquitin E1 activating enzyme, which catalyzes the first step of the Ubiquitin conjugation cascade. UBA1 charges Ubiquitin to a thioester on its active site cysteine through an adenylate intermediate.[1][2][3][4]
Catalog number: SBB-CE0021, 100 μg
UBE2D1 is an E2 conjugating enzyme which catalyzes the E3 mediated ubiquitination of a target substrate. It is known to interact with Parkin, and is involved in PINK1 mediated mitophagy. This protein is recombinantly expressed in E.coli. [1][2]
Catalog number: SBB-CE0027, 100 μg
UBE2D2 is an E2 conjugating enzyme which catalyzes the E3 mediated ubiquitination of a target substrate. It is known to interact with Parkin, and is involved in PINK1 mediated mitophagy. This protein is recombinantly expressed in E.coli. [1][2]
Catalog number: SBB-CE0019, 100 μg
UBE2D3 is an E2 conjugating enzyme which catalyzes the E3 mediated ubiquitination of a target substrate. It is known to interact in conjunction with E3 ligase MDM2 to ubiquitinate p53. This protein is recombinantly expressed in E.coli.[1][2]
Catalog number: SBB-CE0020, 100 μg
UBE2L3. E2 enzyme with specificity towards E3 ligases containing HECT (Homologous to the E6AP Carboxy-terminus) or RBR (Ring in-between ring) domains. This protein is recombinantly expressed in E.coli.[1][2]
Catalog number: SBB-CE0022, 100 μg
Recombinant Human UBE2K (HIP2). E2 enzyme which catalyzes free K48-linked polyubiquitin chains. Known to interact with huntingtin and TRIM6. The protein is N-terminally His-tagged, and recombinantly expressed in E.Coli. [1][2]